CU News

The Microneedle Patch – A Cheap, Safe, and Painless Innovation by CU Engineering Professor

Needle phobia is a common fear for both children and adults. However, with the microneedle patch invented by Chulalongkorn University Mechanical Engineering Professor, Assistant Professor Dr. Werayut Srituravanich, there may very well now be a quick and affordable solution for needle fear.  Through over 4 years of research, Dr. Werayut has developed the microneedle – a small transdermal patch used for drug delivery that is low in cost and safe to use.


Although Dr. Werayut’s microneedle patch is not the first of its kind, it is economical and takes less time to apply. The existing microneedle patches in international markets are made from biodegradable polymer, which slows down the speed medication dissolves into the skin.  Moreover, the microneedle innovation by Dr. Werayut is made from maltose sugar solution, which is less costly to produce. The material can be formed at low temperatures and is easy to dissolve, safe, and affordable.


“Research indicates that between 10-20% of people have needle phobia, 50% of which are children.  Microneedle patches work because the needles are less than 1 millimeter in depth and do not reach the patient’s pain receptor level. The application process is simple.  Patients can place the patch on the skin, then apply light pressure for 5 minutes, delivering  the medication.  This is much faster, compared to the biodegradable polymer, which requires up to 20 minutes of constant pressure for the drugs to dissolve.  Overall, the patch can be used by nurses and reduces the amount of vaccine needed by more than 30%.  The microneedle patch has now been filed for patent by Chulalongkorn University’s Intellectual Property Institute”, says Dr. Werayut.


In addition to the microneedle patches, Dr. Werayut is looking into the development of other forms of vaccination tools, such as hollow syringes and silk microneedles.  The professor pointed out that the microneedle research can be improved to deliver a wide range of medication and be applied in a variety of health-related disciplines.  Collaboration with professors from other faculties, including the Faculty of Medicine, Faculty of Science, and Faculty of Pharmacy, are already underway to extend the research and explore the use of microneedles with  vaccines, insulin, drugs, cosmetics, and Thai herbs.


Dr. Werayut added that, “Apart from the microneedle, the research operation center at the Department of Mechanical Engineering is also exploring other micro-level research applicable to medicine.  One recent innovation, for example, is the Needle Guide, which can be used with ultrasound machines and for people with glaucoma”.

Chula is the place to discover one’s true individuality and the years I spent here were most enjoyable.

Rossukhon Kongket Alumni, Faculty of Communication Arts, Chulalongkorn University